Abstract: Quantitative ultrasound methods are widely investigated as a promising tool for tissue characterization. In this paper, a novel quantitative method is developed which can be used to assess scattering properties of tissues. The proposed method is based on analysis of oscillations of the backscattered echo power spectrum. It is shown that these oscillations of the power spectrum are connected with the distances between scatterers within the medium. Two techniques are proposed to assess the scatterer’s distribution. First, we show that the inverse Fourier transform of the backscattered echo power spectrum corresponds to a histogram of the distances between scatterers. Second, the Hilbert-Huang transform is used to directly extract the power spectrum oscillations. Both methods are examined by means of a numerical experiment. A cellular gas model of a biological medium is considered. Results are presented and discussed. Both methods can be used to evaluate the scatterer’s distribution by means of the power spectrum oscillations.