HYDROACOUSTICS
ANNUAL JOURNAL
START NEW VOL 19 SEARCH STATISTICS PAS - GDANSK DIVISION

Estimation of radial artery reactive response using high frequency ultrasound

pp. 297-306, vol. 19, 2016

Andrzej Nowicki
Department of Ultrasound, Institute of the Fundamental Technological Research, Poland

Wojciech Secomski
Department of Ultrasound, Institute of the Fundamental Technological Research, Poland

Zbigniew Trawiński
Department of Ultrasound, Institute of the Fundamental Technological Research, Poland

Marcin Lewandowski
Department of Ultrasound, Institute of the Fundamental Technological Research, Poland

Ihor Trots
Department of Ultrasound, Institute of the Fundamental Technological Research, Poland

Michał Szubielski
Mazowiecki Szpital Wojewódzki, Poland

Robert Olszewski
Institute of the Fundamental Technological Research Polish Academy of Sciences, Poland

Key words: thick film transducers; atherosclerosis; flow mediated vasodilation

Abstract: Background: There is a growing interest in the application of non-invasive clinical tools allowing one to assess the endothelial function, preceding atherosclerosis. The precision in estimating of the artery Flow Mediated Vasodilation (FMD) using standard 10-12 MHz linear array probes does not exceed 0.2 mm, far beyond that required. Methods: We have introduced a wide-band, high frequency 25-30 MHz, Golay encoded wobbling type imaging to measure dilation of the radial artery instead of the brachial one. 18 young volunteers, and 4 volunteers with cardiac events history, were examined. In the second approach 20 MHz linear scanning combined with 20 MHz pulsed Doppler attached to the linear array was used. The radial artery FMD was normalized using shear rate at the radial artery wall. Results and Conclusions: For the “healthy” group, the FMD resulting from reactive hyperemia response was over 20%; while in the “atherosclerotic” group, the FMD was at least twice as small, not exceeding 10%. The shear rate (SR) normalized FMDSR was in the range from 7.8 to 9.9 in arbitrary units, while in patients with minor cardiac history FMDSR was clearly lower, 6.8 to 7.6. The normalized FMDSR of radial artery RARR can be an alternative to the brachial FMD where the precision of measurements is lower and the diameter dilation does not exceed 7-10%.

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© Polish Acoustical Society - Gdansk Department, Polish Academy of Sciences. This work is licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported. (CC BY-NC-SA 3.0)